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TRIUMPH-3 enrolled adults with established cardiovascular disease and took weight as its primary endpoint, and its pre-specified cardiovascular analyses were inconclusive because events occurred less frequently than anticipated in every arm, with hazard ratios of 0.82 (95 per cent CI 0.55 to 1.22) for five-component MACE and 1.12 (0.64 to 1.96) for three-component MACE
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Low blood sugar (hypoglycemia) – If combined with insulin or other diabetes medications, there’s a risk of dangerously low blood sugar levels
